Does the vitiligo skin color restored means cured ? Whether the Vitiligo can restore the skin color depending on the human hair follicle melancytes. The melancytes ‘s activities is different on the hair follicle area. one of the melancytes have no activity at external of the hair follicle. On skin lesion part, we even can not see the active melancytes. So which means it can not to synthesis the melanin. Vitiligo’s regimentation is that the melancytes at the external of the follicle and the root of the sheath are activated, divided, multiplied. Along the hair follicle from bottom to top, resulting in the vitiligo pigment regeneration, and white patches restored the color.
The studies shown that the the hair root sheath at the external hair follicle exist a lot of melancytes (temporarily nonfunctional melancytes) , under the specific factor can make that activate. This will provide a melancytes reservoir to get white skin color restored. This will explain for those part don’t have the hair follicle structure such as the lips, and distal dorsal, and palm area . that’s the reason why it is hard to restore the skin color. It also due to these part lack of the melancytes reservoir.
Besides that, the normal melancytes at the surrounding of white patches migrate toward the white patches. It is also the mean reason for restoring the skin color. The melancytes are migrate to the white patches epidermis. It will stay at epidermis basal layer. The epidermal melancytes will form the epidermis melanin unit combine with the keratinocytes.
The vitiligo patients should stick to doing treatment, Even after vitiligo is cured, we should still carry on a period of the treatment. It is helpful to prevent disease rebounding again.
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